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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB1
All Species:
19.7
Human Site:
Y11
Identified Species:
30.95
UniProt:
P23443
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23443
NP_003152.1
525
59140
Y11
R
R
R
R
D
G
F
Y
P
A
P
D
F
R
D
Chimpanzee
Pan troglodytes
XP_523815
451
50966
D8
M
R
R
R
R
R
R
D
G
F
Y
P
A
P
D
Rhesus Macaque
Macaca mulatta
XP_001109701
525
59511
Y11
R
R
R
R
D
G
F
Y
P
A
P
D
F
R
D
Dog
Lupus familis
XP_537702
525
59107
Y11
R
R
R
R
D
G
F
Y
P
A
P
D
F
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSK8
525
59199
Y11
R
R
R
R
D
G
F
Y
L
A
P
D
F
R
H
Rat
Rattus norvegicus
P67999
525
59113
Y11
R
R
R
R
D
G
F
Y
P
A
P
D
F
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
S8
M
L
D
T
G
Q
I
S
E
S
M
D
H
G
G
Chicken
Gallus gallus
P18652
752
84421
W10
L
A
Q
L
A
E
P
W
P
N
M
E
L
V
Q
Frog
Xenopus laevis
P10666
629
71268
W10
L
A
Q
L
V
D
L
W
P
E
V
E
L
V
H
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
Q8
M
I
S
F
G
P
A
Q
E
S
S
L
K
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
S31
Q
H
P
R
E
S
E
S
L
A
Y
E
E
P
D
Honey Bee
Apis mellifera
XP_395876
456
51514
L9
A
A
V
F
D
I
E
L
H
D
A
D
T
V
N
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
G17
A
Q
L
G
E
P
F
G
I
T
P
S
S
I
E
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
D9
A
G
H
A
G
V
F
D
L
E
L
C
E
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Q13
C
S
V
A
N
K
N
Q
T
G
K
P
F
Q
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
94.2
99.8
N.A.
99.2
99.6
N.A.
90.2
31.9
36.8
32.2
N.A.
20.8
54.6
31.2
59
Protein Similarity:
100
85.9
95.6
100
N.A.
99.4
99.6
N.A.
90.8
46.6
52.7
46.6
N.A.
31.3
68
43.6
70.8
P-Site Identity:
100
26.6
100
100
N.A.
86.6
93.3
N.A.
6.6
6.6
6.6
0
N.A.
20
13.3
13.3
13.3
P-Site Similarity:
100
26.6
100
100
N.A.
86.6
93.3
N.A.
13.3
26.6
26.6
13.3
N.A.
40
20
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
0
14
7
0
7
0
0
40
7
0
7
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
7
0
40
7
0
14
0
7
0
47
0
0
40
% D
% Glu:
0
0
0
0
14
7
14
0
14
14
0
20
14
0
14
% E
% Phe:
0
0
0
14
0
0
47
0
0
7
0
0
40
0
0
% F
% Gly:
0
7
0
7
20
34
0
7
7
7
0
0
0
7
7
% G
% His:
0
7
7
0
0
0
0
0
7
0
0
0
7
7
20
% H
% Ile:
0
7
0
0
0
7
7
0
7
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
0
7
0
0
0
0
7
0
7
0
7
% K
% Leu:
14
7
7
14
0
0
7
7
20
0
7
7
14
0
0
% L
% Met:
20
0
0
0
0
0
0
0
0
0
14
0
0
7
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
7
0
0
0
0
7
% N
% Pro:
0
0
7
0
0
14
7
0
40
0
40
14
0
14
0
% P
% Gln:
7
7
14
0
0
7
0
14
0
0
0
0
0
7
7
% Q
% Arg:
34
40
40
47
7
7
7
0
0
0
0
0
0
34
0
% R
% Ser:
0
7
7
0
0
7
0
14
0
14
7
7
7
0
0
% S
% Thr:
0
0
0
7
0
0
0
0
7
7
0
0
7
0
0
% T
% Val:
0
0
14
0
7
7
0
0
0
0
7
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
14
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _